Recommended protocols for the Multiple Sleep Latency Test and Maintenance of Wakefulness Test in adults: guidance from the American Academy of Sleep Medicine

[No authors listed] [No authors listed] J Clin Sleep Med. 2022 Aug 1;18(8):2089. doi: 10.5664/jcsm.10100. J Clin Sleep Med. 2022. PMID: 35912580 Free PMC article. No abstract available.

Abstract

This article updates the American Academy of Sleep Medicine protocols for the administration of the Multiple Sleep Latency Test and the Maintenance of Wakefulness Test. The American Academy of Sleep Medicine commissioned a task force of clinical experts in sleep medicine to review published literature on the performance of these tests since the publication of the 2005 American Academy of Sleep Medicine practice parameter paper. Although no evidence-based changes to the protocols were warranted, the task force made several changes based on consensus. These changes included guidance on patient preparation, medication and substance use, sleep before testing, test scheduling, optimum test conditions, and documentation. This article provides guidance to providers who order and administer the Multiple Sleep Latency Test and the Maintenance of Wakefulness Test.

Citation: Krahn LE, Arand DL, Avidan AY, et al. Recommended protocols for the Multiple Sleep Latency Test and the Maintenance of Wakefulness Test in adults: guidance from the American Academy of Sleep Medicine. J Clin Sleep Med. 2021;17(12):2489-2498.

Keywords: Maintenance of Wakefulness Test; Multiple Sleep Latency Test; protocol; sleep testing.

© 2021 American Academy of Sleep Medicine.

Conflict of interest statement

The development of this article was funded by the American Academy of Sleep Medicine. Mr. Harrod is employed by the American Academy of Sleep Medicine. The other authors report no conflicts of interest.

Similar articles

Maski KP, Amos LB, Carter JC, Koch EE, Kazmi U, Rosen CL. Maski KP, et al. J Clin Sleep Med. 2024 Apr 1;20(4):631-641. doi: 10.5664/jcsm.10974. J Clin Sleep Med. 2024. PMID: 38149645

Littner MR, Kushida C, Wise M, Davila DG, Morgenthaler T, Lee-Chiong T, Hirshkowitz M, Daniel LL, Bailey D, Berry RB, Kapen S, Kramer M; Standards of Practice Committee of the American Academy of Sleep Medicine. Littner MR, et al. Sleep. 2005 Jan;28(1):113-21. doi: 10.1093/sleep/28.1.113. Sleep. 2005. PMID: 15700727

Howell M, Avidan AY, Foldvary-Schaefer N, Malkani RG, During EH, Roland JP, McCarter SJ, Zak RS, Carandang G, Kazmi U, Ramar K. Howell M, et al. J Clin Sleep Med. 2023 Apr 1;19(4):769-810. doi: 10.5664/jcsm.10426. J Clin Sleep Med. 2023. PMID: 36515150 Free PMC article.

Caples SM, Anderson WM, Calero K, Howell M, Hashmi SD. Caples SM, et al. J Clin Sleep Med. 2021 Jun 1;17(6):1287-1293. doi: 10.5664/jcsm.9240. J Clin Sleep Med. 2021. PMID: 33704050 Free PMC article. Review.

Tanaka H. Tanaka H. Nihon Rinsho. 2015 Jun;73(6):971-9. Nihon Rinsho. 2015. PMID: 26065128 Review. Japanese.

Cited by

Giannaki CD, Sakkas GK, Hadjigeorgiou GM, Manconi M, Bargiotas P. Giannaki CD, et al. Eur J Appl Physiol. 2024 Sep;124(9):2547-2560. doi: 10.1007/s00421-024-05556-6. Epub 2024 Jul 20. Eur J Appl Physiol. 2024. PMID: 39031176 Free PMC article. Review.

Zeng S, Feng F, Li W, Xu Y, Zhao R, Liang S, Cheng Y, Fang R, Jia H, Wang Y, Lv D, Zhang B. Zeng S, et al. J Clin Sleep Med. 2024 Aug 1;20(8):1349-1355. doi: 10.5664/jcsm.11168. J Clin Sleep Med. 2024. PMID: 38648114

Fang R, Cheng Y, Li F, Xu Y, Li Y, Liu X, Guo S, Wang Y, Jiang J, Zhou D, Zhang B. Fang R, et al. Nat Sci Sleep. 2024 Mar 20;16:305-313. doi: 10.2147/NSS.S450578. eCollection 2024. Nat Sci Sleep. 2024. PMID: 38533251 Free PMC article.

Tang M, Huang S, Guo W, Zhou J, Huang Z, Li W, Sun Q, Wang Z. Tang M, et al. Front Immunol. 2023 Dec 20;14:1302514. doi: 10.3389/fimmu.2023.1302514. eCollection 2023. Front Immunol. 2023. PMID: 38173730 Free PMC article.

Maski KP, Amos LB, Carter JC, Koch EE, Kazmi U, Rosen CL. Maski KP, et al. J Clin Sleep Med. 2024 Apr 1;20(4):631-641. doi: 10.5664/jcsm.10974. J Clin Sleep Med. 2024. PMID: 38149645

References

    1. Carskadon MA, Dement WC . The Multiple Sleep Latency Test: what does it measure? Sleep. 1982. ; 5 ( Suppl 2 ): S67 – S72 . - PubMed
    1. Mitler MM, Gujavarty KS, Browman CP . Maintenance of Wakefulness Test: a polysomnographic technique for evaluation treatment efficacy in patients with excessive somnolence . Electroencephalogr Clin Neurophysiol. 1982. ; 53 ( 6 ): 658 – 661 . - PMC - PubMed
    1. Arand D, Bonnet M, Hurwitz T, Mitler M, Rosa R, Sangal RB . The clinical use of the MSLT and MWT . Sleep. 2005. ; 28 ( 1 ): 123 – 144 . - PubMed
    1. American Academy of Sleep Medicine . International Classification of Sleep Disorders. 3rd ed. Darien, IL: : American Academy of Sleep Medicine; ; 2014. .
    1. Sangal RB, Thomas L, Mitler MM . Maintenance of Wakefulness Test and Multiple Sleep Latency Test. Measurement of different abilities in patients with sleep disorders . Chest. 1992. ; 101 ( 4 ): 898 – 902 . - PubMed